IJIRST (International Journal for Innovative Research in Science & Technology)ISSN (online) : 2349-6010

 International Journal for Innovative Research in Science & Technology

Synthesis, Structure-Parameter Correlation And Biological Evaluation Of 1-(2-Chloro-5-Nitrophenyl)-3-Phenyl-2-Propenone Compounds.


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International Journal for Innovative Research in Science & Technology
Volume 2 Issue - 7
Year of Publication : 2015
Authors : C.Balamurugan

BibTeX:

@article{IJIRSTV2I7037,
     title={Synthesis, Structure-Parameter Correlation And Biological Evaluation Of 1-(2-Chloro-5-Nitrophenyl)-3-Phenyl-2-Propenone Compounds.},
     author={C.Balamurugan},
     journal={International Journal for Innovative Research in Science & Technology},
     volume={2},
     number={7},
     pages={49--60},
     year={},
     url={http://www.ijirst.org/articles/IJIRSTV2I7037.pdf},
     publisher={IJIRST (International Journal for Innovative Research in Science & Technology)},
}



Abstract:

A series of 1-(2-chloro-5-nitrophenyl)-3-phenyl-2-propenones were synthesized from 2-chloro-5-nitroacetophenone with various substituted benzaldehydes by crossed-Aldol condensation. The synthesized compounds have been characterized by their physical constants and spectral data. The antimicrobial activities of synthesized 1, 3-diphenyl-2-propenone compounds have been evaluated by Kirby-Baur disc diffusion method using their respective antibacterial and fungal strains.


Keywords:

Crossed-Aldol condensation; 2-Chloro-5-nitrophenyl chalcones; IR and NMR spectra; Substituent effects; Antimicrobial activities


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